The variety of his work allowed him to gain wide-spread experiences in different areas of music, such as opera, operetta, ballet, musical, symphony, chamber music, movie scores and dance music. These experiences enable him to perform within an exceptionally large spectrum ranging from symphonic orchestras to big band. Numerous radio, CD and television productions were created under the direction of Lothar Seyfarth.
Guest appearances abroad led him to almost all countries within Europe as well as to Cuba, North Korea, the former Soviet Union and Australia. His symphonic repertoire encompasses more than 100 pieces from almost 240 composers, among them about 70 composers of the 20th century. Lothar Seyfarth is intensively committed to the reconstruction and performance of forgotten compositions. Since the 2004/2005 season, he is Honorary Conductor of the Vogtland Philharmonic Orchestra Greiz/Reichenbach.